JULÄINE Treatment on Harley Street, Marylebone

At Dr Azadeh’s clinic, Julaine is offered as a poly-L-lactic acid (PLLA) collagen biostimulator designed to restore firmness, smoothness, and structural support from within. Rather than adding immediate volume in the way a traditional filler does, Julaine works beneath the skin’s surface to reawaken the body’s own collagen-building processes, gradually improving elasticity and definition over the weeks that follow treatment.

As collagen rebuilds, skin becomes firmer, more resilient, and visibly refreshed — with results that can last up to two years.

Julaine suits patients who want a natural, gradual improvement rather than the more immediate, sometimes overfilled look associated with dermal fillers.

Treatment is carried out personally by Dr Azadeh, combining clinical precision with an artistic eye for facial balance.

Why London Patients Choose Julaine with Dr Azadeh

Trusted Harley Street location with a reputation for medical integrity
One-to-one treatment with a GMC-registered GP with 15+ years’ experience
Use of high-purity, evenly sized PLLA microspheres for predictable, non-inflammatory results
Focus on rebuilding skin structure, not adding artificial volume
Results that develop gradually, avoiding an overfilled or “done” appearance
Suitable for patients not ready for fillers but wanting visible improvement
Patients travel from Marylebone, Fitzrovia, Mayfair and beyond for treatment

“Dr. Azadeh is simply the best doctor in London. She is warm and caring and made me feel so comfortable. So happy I found her clinic.” – April 2025

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Let’s assess your skin together and explore a treatment plan that works from within.

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What Is Julaine: A Regenerative Approach to Ageing

Julaine is a collagen-stimulating injectable made from highly purified PLLA microspheres. Rather than plumping or filling, it triggers a biological repair process — prompting fibroblasts to generate new collagen and elastin, gradually restoring the skin’s own structural support.

This makes it ideal for clients experiencing:

  • Loss of firmness, tone, or elasticity
  • Nasolabial folds, marionette lines, or deeper facial folds
  • Volume loss through ageing or weight change
  • A desire for natural-looking rejuvenation without an overfilled appearance
  • Skin that needs structural support rather than surface correction

How Julaine Works

Julaine uses evenly sized, high-purity PLLA microspheres injected into the dermis. Dr Azadeh places small amounts of the product into areas where collagen support has diminished. As the microspheres gradually break down, they stimulate fibroblasts to produce new type I and type III collagen fibres, rebuilding structure from within.

The result is firmer, more resilient skin – not an artificial alteration.

Areas That Respond Well to Julaine Treatment

Nasolabial Folds: Softens smile lines, restores support

Marionette Lines: Smooths and lifts the lower face

Cheeks & Temples: Rebuilds volume and contour

Jawline & Chin: Defines and firms

Neck & Décolletage: Improves firmness and skin quality

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Your Skin Regeneration Plan

Each session begins with a conversation. At your first appointment, Dr Azadeh will evaluate your skin using a whole-health approach – taking into account age, skin history, lifestyle, and any factors that may be influencing your skin’s collagen quality and structural support.

Treatment typically involves:

  • A short series of injections using a fine needle or cannula
  • 2 to 3 sessions, spaced 4-6 weeks apart
  • Results that gradually build over 6-12 weeks
  • No added volume – just firmer, better-structured skin

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FAQs: Julaine Treatment on Harley Street


No. Although Julaine is administered via small injections, it is not a dermal filler and does not add volume to the face.

Julaine is a polynucleotide treatment that works by stimulating your skin’s natural repair processes. Once injected, the polynucleotides activate fibroblasts – the cells responsible for producing collagen and elastin. This encourages healthier, stronger skin from within, improving hydration, firmness, elasticity and overall skin quality without changing your natural facial contours.

Because Julaine enhances skin rather than filling it, it is an excellent option for patients seeking subtle, natural-looking rejuvenation.


How soon will I see results from Julaine?

Julaine works by stimulating collagen production rather than creating an instant filling effect, so results develop gradually.

Many patients notice improvements in skin hydration and radiance within two to four weeks, while collagen and elastin production continues over the following months. The skin typically becomes firmer, smoother and more resilient as regeneration progresses.


Yes. Julaine is a clinically developed polynucleotide treatment with an excellent safety profile when administered by an experienced medical professional.

At our Harley Street clinic, every treatment is performed by a qualified doctor following a detailed consultation to ensure Julaine is appropriate for your skin concerns and aesthetic goals. As with any injectable treatment, temporary redness, swelling or bruising can occur but usually settles quickly.


Most patients enjoy results for around six to nine months, although this varies depending on age, skin quality and lifestyle factors.

For the best outcome, we typically recommend an initial course of treatments followed by maintenance sessions every six to nine months to continue stimulating collagen production and maintaining healthier, more youthful-looking skin.


A typical Julaine appointment takes approximately 45 to 60 minutes, including your consultation, treatment and aftercare advice.

The injections themselves are relatively quick, making Julaine a convenient treatment that can often fit into a lunch break.


Downtime following Julaine treatment is minimal.

You may experience mild redness, swelling, small injection bumps or slight bruising immediately after treatment, but these effects usually resolve within a few hours to a couple of days. Most patients return to work and normal daily activities straight away, although we recommend avoiding strenuous exercise, excessive heat and alcohol for the first 24 hours.

Schedule Your Julaine Consultation on Harley Street

Your skin is more than just the surface – and real change starts deeper. If you’re looking for a treatment that works with your body’s natural healing mechanisms to rebuild long-term structure, Julaine offers an intelligent, regenerative solution.

Your care. Your confidence. Your clinic.

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Celina Lighton
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Dr Ovaici was recommended to me for her private GP service and I thought she was great. Very thorough and sensible advice. 5 stars!!
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L. Alo.
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Dr. Azadeh is simply the best doctor in London. She is warm and caring and made me feel so comfortable. So happy I found her clinic.
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Homa Ovaici
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I cannot recommend Dr. Azadeh Ovaici highly enough! From start to finish, my experience with her was absolutely flawless. She is not only incredibly knowledgeable and skilled in her craft but also has such a warm and attentive manner that immediately put me at ease. Dr. Ovaici took the time to understand exactly what I was looking for and explained every step of the process in detail, ensuring I felt comfortable and confident throughout. Her attention to detail and expertise are unmatched, and I could not be happier with the results. It’s rare to find someone who combines such professionalism with genuine care for their patients, but Dr. Ovaici truly excels in both areas. If you’re looking for an aesthetic practitioner who is both talented and compassionate, look no further—she’s simply the best!
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Faïza S'Lika
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The best doctor in the kensington area - On top of being a top notch professional Dr Azadeh is the kindest, most devoted, and dedicated Doctor I had the chance to have since I moved to London.
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Sahrin Rahman
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I tried to get some urgent treatment arranged by my NhS Gp for my son but was told even though it was an emergency it would take weeks just to get a paper referral . Being registered with Dr Ovaici has been amazing as she was able to arrange everything promptly . The service was polite , prompt and efficient and I cannot recommend her enough .
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L R
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Dr Azadeh is exceptional at her job. She’s really knowledgeable and a safe pair of hands whilst also keeping up to date with latest innovations in treatments. She has a generous and kind demeanour, really listens to what you want and helps you achieve it. I came to her having tried out many other dermatologists/ aestheticians and she is by far and away the best. I love her holistic approach to health and beauty.
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Sheila Nguyen
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I saw Dr Ovaici and she was kind, understanding and supportive. Dr Ovaici gave me advice and helped me with treatment quickly. Really happy with the service and would highly recommend
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Abdelhack C
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Dr Ovaici is the best doctor I have met. She is a kind, caring, empathetic and seems to be 100% genuine. She took time to listen to me during a time of hardship and made me feel at ease. Dr Ovaici is a asset to the surgery. I honestly feel that she has my best interest at heart and I hope she is appreciated by all. Thanks a million Dr Ovaici.
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L Z
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If you're searching for a top-notch clinic with exceptional medical care, look no further. My recent experience at The Kensington General Practice was nothing short of outstanding. From the moment I walked in, I was greeted by a warm and friendly staff who made me feel comfortable and at ease. The clinic itself is spotless, modern, and equipped with state-of-the-art facilities. Dr. Ovaici is truly a remarkable physician. Not only is she incredibly knowledgeable and experienced, but her compassionate approach is what sets her apart. She took the time to listen to all of my concerns, thoroughly explained every aspect of my treatment plan, and answered all my questions with patience and clarity. I highly recommend Dr. Ovaici to anyone in need of medical or aesthetic care. You can trust that you will be in the best of hands!